Other

Patents

Asymmetric Suzuki Reactions Ltd.

Company number: 11837583. Incorporated 19 February 2019
S. M. Morrow CEO

Kinetic asymmetric resolution of racemic compounds

GB1815018.5

Ligands and catalysts

GB1710941.4
US/2019/0009259

Asymmetric synthesis of organic compounds

PCT/GB2012/052537
WO/2013/054131
US-14/351,240
EU-1277505.3

Catalysts, ligands and use thereof

EP2986375
US 2016/0074852

Asymmetric synthesis of chiral compounds

WO2015008097
GB1312991.1
PTC/GB2014/052230

Asymmetric addition reactions

EP3307698
US 2018/0334414 A1

Manchester with Jonathan Clayden

21) Synthesis of enantiomerically enriched (R)-13C-labelled 2-aminoisobutyric acid (Aib) by conformational memory in the alkylation of a derivative of L-alanine

S. P. Fletcher, J. Solà, D. Holt, R. A. Brown, J. Clayden

20) Nanometer-range communication of stereochemical information by reversible switching of molecular helicity

J. Solà, S. P. Fletcher, A. Castellanos, J. Clayden

Angew. Chem. 2010, 49, 6836–6839

19) Hindered diarlyether and diarylsulfone bisphosphine ligands: atropisomerism and metal complexes

J. Clayden, S. P. Fletcher, J. Senior, C. P. Worrall

Special Issue dedicated to Professor Henri B. Kagan on the occasion of his 80th birthday

Tetrahedron Asymmetry 2010, 21, 1355–1360

18) Conformational preferences of a polar biaryl: A phase- and enantiomeric purity- dependent molecular hinge

J. Clayden, S. P. Fletcher, S. J. M. Rowbottom, M. Helliwell

Org. Lett. 2009, 11, 2313–2316

17) Controlling axial conformation in 2-arylpyridines and 1-arylisoquinolines: Application to the asymmetric synthesis of QUINAP by dynamic thermodynamic resolution

J. Clayden, S. P. Fletcher, J. J. W. McDouall, S. J. M. Rowbottom

J. Am. Chem. Soc. 2009, 110, 5331–5343

Groningen with Ben Feringa

16) Catalytic enantioselective synthesis of naturally occurring butenolides via hetero-allylic alkylation and ring closing metathesis

B. Mao, K. Geurts, M. Fañanás-Mastral, A. W. van Zijl, S. P. Fletcher, A. J. Minnaard, B. L. Feringa

Org. Lett. 2011, 13, 948–951

15) Copper catalyzed asymmetric allylic substitution reactions with organozinc and Grignard reagents

K. Geurts, S. P. Fletcher, A. W. van Zijl, A. J. Minaard, B. L. Feringa

Pure Appl. Chem. 2008, 80, 1025–1037

14) An astrophysically-relevant mechanism for amino acid enantiomer enrichment

S. P. Fletcher, R. B. C. Jagt, B. L. Feringa

Cover Article

Chem. Commun. 2007, 2578–2580

13) Cu–catalyzed asymmetric synthesis of chiral allylic esters

K. Geurts, S. P. Fletcher, B. L. Feringa

J. Am. Chem. Soc. 2006, 128, 15572–15573

12) Catalytic asymmetric synthesis of acyclic arrays by tandem 1,4–addition–aldol reactions

G. P. Howell, S. P. Fletcher, K. Geurts, B. ter Horst and B. L. Feringa

J. Am. Chem. Soc. 2006, 128, 14977–14985

11) A reversible, unidirectional molecular rotary motor driven by chemical energy

S. P. Fletcher, F. Dumur, M. M. Pollard, B. L. Feringa

Science 2005, 310, 80–82

Postgraduate

10) Synthesis of diverse 2,3-dihydroindoles, 1,2,3,4-tetrahydro-quinolines and benzo-fused azepines by formal radical cyclization onto aromatic rings

D. L. J. Clive, J. Peng, S. P. Fletcher, V. Ziffle, D. A. Wingert

J. Org. Chem. 2008, 73, 2330–2344

9) Oxidation of p–aminophenols and formal radical cyclization onto benzene rings: Formation of benzo–fused nitrogen heterocycles

S. P. Fletcher, D. L. J. Clive, D. A. Wingert, J. Peng

Org. Lett. 2005, 7, 23–26

8) Formal radical cyclization onto benzene rings – a general method and its use in the synthesis of ent–norcardione A

D. L. J. Clive, S. P. Fletcher, D. Liu

J. Org. Chem. 2004, 69, 3282–3293

7) Synthesis of (+)–nocardione A – use of formal radical cyclization onto a benzene ring

D. L. J. Clive, S. P. Fletcher

Chem. Commun. 2003, 2464–2465

6) Formal radical cyclization onto benzene rings – a general method proceeding via cross–conjugated dienones

D. L. J. Clive, S. P. Fletcher, M. Zhu

Chem. Commun. 2003, 526–527

5) Synthesis of the bicyclic dienone core of the antitumor agent ottelione B

D. L. J. Clive, S. P. Fletcher

Chem. Commun. 2002, 1940–1941

Undergraduate

4) Structure/function studies for in vitro chemical inhibition of Fc–receptor–mediated phagocytosis

A. H. Foo, S. P. Fletcher, R. F. Langler, C. H. Porter, D. R. Branch

Transfusion 2007, 47, 290-298

3) The S2 oxygen atoms are essential for the pronounced fungitoxitity of the sulfur–rich natural product, dysoxysulfone

S. A. Bewick, S. Duffy, S. P. Fletcher, R. F. Langler, H. G. Morrison, E. M. O'Brien, C. Ross, V. C. Stephenson

Aust. J. Chem. 2005, 58, 218–223

2) Novel disulfides with antitumor efficacy and specificity

R. Griffiths, W. W.–L. Wong, S. P. Fletcher, L. Z. Penn, R. F. Langler

Aust. J. Chem. 2005, 58, 128–136

1) Dioxomolybdenum (VI) complexes containing 1–alkyl–3– hydroxy–2–ethyl–4–pyridinones

N. C. Tam, S. P. Fletcher, C. M. Vogels, S. A. Westcott, A. Decken

Transit. Met. Chem. 2003, 28, 103–109